- A Case of Combined hepatocellular carcinoma and cholangiocarcinoma (CHC) without underlying liver disease.
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Jae Hoon Jung, Jung Il Kim, Sun Hyung Kang, Seok Hee Moon, Seok Hyun Kim, Byung Seok Lee, Heon Young Lee, Joon Sik Cho, Kyung Sook Shin, Dae Young Kang, Hyun Mo Kang
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Journal of the Korean Liver Cancer Study Group. 2007;7(1):62-65. Published online June 30, 2007
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Abstract
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- Combined hepatocellular carcinoma and cholangiocarcinoma (CHC) is a rare form of primary liver cancer having
features of both hepatocelluar and biliary epithelial differentiation and is related to cirrhosis. Recently, a 64-oldmale
who was admitted to our hospital for evaulation of hepatic mass which was detected on ultrasonography.
He had no underlying cirrhosis. Based on serologic findings of high alpha-fetoprotein(AFP) level, a preoperative
diagnosis of hepatocellular carcinoma was made. A right lobectomy was done. On histologic examination, the
resected tumor was shown to consist of two different tissues. On immunohistochemistry, the tumor is postitive
for both anti-hepatocyte, CK-7 and CK-19. Finally we confirm combined hepatocellular carcinoma and
cholangiocarcinoma (CHC).
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